WHO was agitating over the slavery issue? I don't think it was southern states attempting to go up north and tell them how to conduct their business until abolitionists in the north had been pushing the south for a few decades. Then when the South finally pushed back, it was somehow their fault?
Back when he was in Congress, for example, Robert Barnwell Rhett of South Carolina and the Charleston Mercury, a noted pro-slavery man and Fire-Eater, voted against the Fugitive Slave Act of 1850 because he thought it was unconstitutional and a major violation of "state's rights". In truth, it probably was the greatest violation of the concept of "state's rights" since the Alien & Sedition Acts of the Thomas Jefferson administration -- but Southerners pushed it because it favored them and it was not their "state's rights" that would be violated.
The Chief Justice Taney's Opinion in the Dred Scott decision was more of the same. If followed, his opinion would shove slavery down the throat of every state in the Union, forever.
But all this seems to be drifting far away from the topic of the thread. Maybe we should get back to Tariffs.